SDCCAG8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-27499

Novus Biologicals, part of Bio-Techne
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NBP2-27499
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all SDCCAG8 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-TINDQSQYIHHLEAE corresponding to internal region according to NP_006633.1.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for SDCCAG8 Antibody

Western Blot: SDCCAG8 Antibody [NBP2-27499]

Western Blot: SDCCAG8 Antibody [NBP2-27499]

Western Blot: SDCCAG8 Antibody [NBP2-27499] - (0.3 ug/ml) staining of HepG2 lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for SDCCAG8 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Peptide ELISA

Detection limit 1:128000

Western Blot

0.3 - 1 ug/ml
Application Notes
WB: Approx. 80 kDa band observed in HEK293 lysates (calculated MW of 82.7 kDa band according to NP_006633.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SDCCAG8

SDCCAG8 is a gene that codes for a protein with four isoforms, with weights of 713, 360, 634, and 669 amino acids and weights of approximately 83, 41, 73, and 78 kDa respectively. The protein coded by SDCCAG8 helps in the formation of epithelial lumen as well as the establishment of cell polarity and is expressed in the thymus, prostate, testis, ovary, small intestine and mucosa as well as in colon and renal cancer tumors. Current studies are being done on several diseases and disorders linked to this gene including colon cancer, Senior-Loken syndrome, Bardet-Biegl syndrome, retinitis, nystagmus, eye disease, polydactyly, multiple sclerosis, and prostatitis. SDCCAG8 has also been shown to have interactions with TSC1, TRAF6, ALMS1, CEP152, and CEP164 in pathways such as the centrosome maturation, cell cycle, and G2/M transition pathways.

Alternate Names

CCCAPAntigen NY-CO-8, Centrosomal colon cancer autoantigen protein, hCCCAP, NPHP10, NY-CO-8, serologically defined colon cancer antigen 8, SLSN7

Entrez Gene IDs

76816 (Mouse); 305002 (Rat)

Gene Symbol

SDCCAG8

UniProt

NP_006633.1 (Human)

Additional SDCCAG8 Products

Product Documents for SDCCAG8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SDCCAG8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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