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SDHC Antibody (3E2)

Novus Biologicals, part of Bio-Techne | Catalog # H00006391-M01

Novus Biologicals, part of Bio-Techne
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H00006391-M01

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 3E2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

SDHC (AAH33626, 1 a.a. ~ 169 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAALLLRHVGRHCLRAHFSPQLCIRNAVPLGTTAKEEMERFWNKNIGSNRPLSPHITIYSWSLPMAMSICHRGTGIALSAGVSLFGMSALLLPGNFESYLELVKSLCLGPALIHTAKFALVFPLMYHTWNGIRHLMWDLGKGLKIPQLYQSGVVVLVLTVLSSMGLAAM

Specificity

SDHC - succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for SDHC Antibody (3E2)

Immunohistochemistry-Paraffin: SDHC Antibody (3E2) [H00006391-M01]

Immunohistochemistry-Paraffin: SDHC Antibody (3E2) [H00006391-M01]

Immunohistochemistry-Paraffin: SDHC Antibody (3E2) [H00006391-M01] - Analysis of monoclonal antibody to SDHC on formalin-fixed paraffin-embedded human skeletal muscle. Antibody concentration 3 ug/ml.
Immunohistochemistry-Paraffin: SDHC Antibody (3E2) [H00006391-M01]

Immunohistochemistry-Paraffin: SDHC Antibody (3E2) [H00006391-M01]

Immunohistochemistry-Paraffin: SDHC Antibody (3E2) [H00006391-M01] - Analysis of monoclonal antibody to SDHC on formalin-fixed paraffin-embedded human skeletal muscle. Antibody concentration 3 ug/ml.

Applications for SDHC Antibody (3E2)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against recombinant protein for WB. It has been used for IHC-P and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SDHC

This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Alternate Names

Integral membrane protein CII-3, mitochondrial, PGL3, QPs1, QPs-1, SDH3, succinate dehydrogenase complex, subunit C, integral membrane protein, 15kD, succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa, succinate-ubiquinone oxidoreducatase cytochrome B large subunit

Entrez Gene IDs

6391 (Human)

Gene Symbol

SDHC

OMIM

602413 (Human)

Additional SDHC Products

Product Documents for SDHC Antibody (3E2)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SDHC Antibody (3E2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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