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SDS3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-48751

Novus Biologicals, part of Bio-Techne
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NBP2-48751
NBP2-48751-25ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KAAVKEFEDKKVELKENLIAELEEKKKMIENEKLTMELTGDSMEVKPIMTRKLRRRPNDPVPIPDKRRKPAPAQLNYLLTDEQIMEDLRTLNKLKSPKRPA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SDS3 Antibody

Western Blot: SDS3 Antibody [NBP2-48751]

Western Blot: SDS3 Antibody [NBP2-48751]

Western Blot: SDS3 Antibody [NBP2-48751] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10
Lane 2: Human cell line RT-4
Lane 3: Human cell line U-251MG sp
Immunohistochemistry-Paraffin: SDS3 Antibody [NBP2-48751]

Immunohistochemistry-Paraffin: SDS3 Antibody [NBP2-48751]

Immunohistochemistry-Paraffin: SDS3 Antibody [NBP2-48751] - Staining of human thyroid gland shows strong nuclear positivity in glandular cells.

Applications for SDS3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SDS3

SDS3 is a subunit of the histone deacetylase-dependent SIN3A corepressor complex. The SIN3A corepressor complex functions to repress transcription through its interaction with histone deacetylases HDAC1 and HDAC2. SDS3 has been demonstrated to play a role in pericentric heterochromatin

Alternate Names

45 kDa Sin3-associated polypeptide, FLJ00052, SAP45suppressor of defective silencing 3 homolog (SDS3, S. cerevisiae), SDS3MGC104711, sin3 histone deacetylase corepressor complex component SDS3, sin3A-associated protein, 45kDa, suppressor of defective silencing 3 homolog (S. cerevisiae), Suppressor of defective silencing 3 protein homolog

Gene Symbol

SUDS3

Additional SDS3 Products

Product Documents for SDS3 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SDS3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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