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SEC11C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80774

Novus Biologicals, part of Bio-Techne
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NBP1-80774
NBP1-80774-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MVRAGAVGAHLPASGLDIFGDLKKMNKRQLYYQV

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (88%), Rat (88%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SEC11C Antibody

Western Blot: SEC11C Antibody [NBP1-80774]

Western Blot: SEC11C Antibody [NBP1-80774]

Western Blot: SEC11C Antibody [NBP1-80774] - Analysis in control (vector only transfected HEK293T lysate) and SEC11C over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).
Immunohistochemistry-Paraffin: SEC11C Antibody [NBP1-80774]

Immunohistochemistry-Paraffin: SEC11C Antibody [NBP1-80774]

Immunohistochemistry-Paraffin: SEC11C Antibody [NBP1-80774] - Staining of human Pancreas shows strong positivity in endoplasmic reticulum in exocrine glandular cells.
Western Blot: SEC11C Antibody [NBP1-80774]

Western Blot: SEC11C Antibody [NBP1-80774]

Western Blot: SEC11C Antibody [NBP1-80774] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

Applications for SEC11C Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50-1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SEC11C

SEC11C is a component of the microsomal signal peptidase complex which removes signal peptides from nascent proteins asthey are translocated into the lumen of the endoplasmic reticulum

Alternate Names

EC 3.4, Microsomal signal peptidase 21 kDa subunit, SEC11 homolog C, SEC11 homolog C (S. cerevisiae), SEC11L3, SEC11-like protein 3, signal peptidase complex catalytic subunit SEC11C, SPase 21 kDa subunit, SPC21SEC11-like 3 (S. cerevisiae), SPCS4CSEC11-like 3

Entrez Gene IDs

90701 (Human)

Gene Symbol

SEC11C

Additional SEC11C Products

Product Documents for SEC11C Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SEC11C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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