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SEC24C Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-81550

Novus Biologicals, part of Bio-Techne
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NBP1-81550
NBP1-81550-25ul

Key Product Details

Validated by

Orthogonal Validation, Independent Antibodies

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: RLPSMTGPLLPGQSFGGPSVSQPNHVSSPPQALPPGTQMTGPLGPLPPMHSPQQPGYQPQQNGSFGPARGPQSNYGGPYPAAPTF

Reactivity Notes

Reactivity reported in scientific literature (PMID: 24743550)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SEC24C Antibody

Western Blot: SEC24C Antibody [NBP1-81550]

Western Blot: SEC24C Antibody [NBP1-81550]

Western Blot: SEC24C Antibody [NBP1-81550] - Analysis in human cell lines PC-3 and HeLa. Corresponding RNA-seq data are presented for the same cell lines. Loading control: Anti-HSP90B1.
Western Blot: SEC24C Antibody [NBP1-81550]

Western Blot: SEC24C Antibody [NBP1-81550]

Western Blot: SEC24C Antibody [NBP1-81550] - Analysis using Anti-SEC24C antibody NBP1-81550 (A) shows similar pattern to independent antibody NBP1-81549 (B).
Immunocytochemistry/ Immunofluorescence: SEC24C Antibody [NBP1-81550]

Immunocytochemistry/ Immunofluorescence: SEC24C Antibody [NBP1-81550]

Immunocytochemistry/Immunofluorescence: SEC24C Antibody [NBP1-81550] - Staining of human cell line U-251 MG shows localization to nucleoplasm and vesicles. Antibody staining is shown in green.

Applications for SEC24C Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SEC24C

The protein encoded by the SEC24C gene is a member of the SEC24 subfamily of the SEC23/SEC24 family, which is involved in vesicle trafficking. The encoded protein has similarity to yeast Sec24p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The product of this gene may play a role in shaping the vesicle, as well as in cargo selection and concentration. Alternatively spliced transcript variants encoding the same protein have been identified. (provided by RefSeq)

Alternate Names

KIAA0079SEC24-related protein C, protein transport protein Sec24C, SEC24 (S. cerevisiae) related gene family, member C, SEC24 family, member C (S. cerevisiae), SEC24 related gene family, member C

Gene Symbol

SEC24C

Additional SEC24C Products

Product Documents for SEC24C Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SEC24C Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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