Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse, Rat

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Secernin-1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 20 amino acid synthetic peptide near the carboxy terminus of human SCRN1. The immunogen is located within amino acids 320 - 370 of SCRN1. Amino Acid Squence: CPAKKEPRFQEKPDRRHELYK

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Secernin-1 Antibody - BSA Free

Immunohistochemistry-Paraffin: Secernin-1 Antibody - BSA Free [NBP1-77187]

Immunohistochemistry-Paraffin: Secernin-1 Antibody - BSA Free [NBP1-77187]

Immunohistochemistry-Paraffin: Secernin-1 Antibody [NBP1-77187] - Human kidney tissue with Secernin-1 antibody at 5 ug/mL.
Secernin-1 Antibody - BSA Free

Western Blot: Secernin-1 Antibody - BSA Free [NBP1-77187] -

Western Blot: Secernin-1 Antibody - BSA Free [NBP1-77187] - Western blot analysis of SCRN1 in human kidney tissue lysate with SCRN1 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.
Secernin-1 Antibody - BSA Free

Immunocytochemistry/ Immunofluorescence: Secernin-1 Antibody - BSA Free [NBP1-77187] -

Immunocytochemistry/ Immunofluorescence: Secernin-1 Antibody - BSA Free [NBP1-77187] - Immunofluorescence of Secernin-1 in Human Kidney cells with Secernin-1 antibody at 20 ug/mL.

Applications for Secernin-1 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Secernin-1

SCRN1 was first identified as a cytosolic protein that is involved in the regulation of exocytosis from peritoneal mast cells. More recent studies have shown that SCRN1 expression is upregulated in gastric cancer cell lines and may possess epitopes that could function as tumor-associated antigens, potentially providing targets for cancer vaccines in the treatment of gastric cancers. Another report indicates that decreased expression of SCRN1 via RNAi expression resulted in significantly lower rates of cell growth in colorectal cancer cell lines, and increased SCRN1 expression in patients with colorectal cancer correlated with poor prognosis, suggesting that SCRN1 may also be involved in the regulation of cell growth and might be useful as a prognostic tool.

Alternate Names

KIAA0193SES1, secernin 1, secernin-1

Gene Symbol

SCRN1

UniProt

NP_001138985 (Human)

Additional Secernin-1 Products

Product Documents for Secernin-1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Secernin-1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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