SECISBP2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-92375

Novus Biologicals, part of Bio-Techne
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NBP1-92375
NBP1-92375-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SECISBP2 Antibodies »

Product Summary for SECISBP2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SEGIKLSADVKPFVPRFAGLNVAWLESSEACVFPSSAATYYPFVQEPPVTEQKIYTEDMAFGASTFPPQYLSSEITLHPYAYSPYTLDSTQNVYSVPGSQYLYNQPSCYRGFQTVKHRNENT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SECISBP2 Antibody

Immunohistochemistry-Paraffin: SECISBP2 Antibody [NBP1-92375]

Immunohistochemistry-Paraffin: SECISBP2 Antibody [NBP1-92375]

Immunohistochemistry-Paraffin: SECISBP2 Antibody [NBP1-92375] - Staining of human fallopian tube shows nuclear and cytoplasmic positivity in glandular cells.

Applications for SECISBP2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SECISBP2

SECISBP2 is an RNA binding protein that interacts with the Sec insertion sequence (SECIS) element in selenoprotein mRNAs. The incorporation of selenocysteine into a protein requires the concerted action of an mRNA element called a sec insertion sequence (SECIS), a selenocysteine-specific translation elongation factor and a SECIS binding protein. With these elements in place, a UGA codon can be decoded as selenocysteine. Mutations in the SECISBP2 gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism.

Alternate Names

DKFZp686C09169, SBP2SECIS-binding protein 2, SECIS binding protein 2, selenocysteine insertion sequence binding protein 2, selenocysteine insertion sequence-binding protein 2

Gene Symbol

SECISBP2

Additional SECISBP2 Products

Product Documents for SECISBP2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SECISBP2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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