Secretory phospholipase A2 Type V Antibody (3G1)

Novus Biologicals, part of Bio-Techne | Catalog # NB100-74433

Novus Biologicals, part of Bio-Techne
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NB100-74433
NB100-74433-0.025mg
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 3G1

Concentration

1 mg/ml

View all Secretory phospholipase A2 Type V Antibodies »

Product Specifications

Immunogen

Full length W79A human group V phospholipase A2.

Reactivity Notes

Human reactivity reported in scientific literature (PMID: 10868798). Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Specificity

Group V Secretory Phospholipase A2 (3G1)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Secretory phospholipase A2 Type V Antibody (3G1)

Immunofluorescence: Secretory phospholipase A2 Type V Antibody (3G1) [NB100-74433]

Immunofluorescence: Secretory phospholipase A2 Type V Antibody (3G1) [NB100-74433]

Immunofluorescence: Secretory phospholipase A2 Type V Antibody (3G1) [NB100-74433] - IF analysis using this antibody.

Applications for Secretory phospholipase A2 Type V Antibody (3G1)

Application
Recommended Usage

Western Blot

1:1000
Application Notes
WB: Detects an approx. 15 kDa band representing Group V Secretory Phospholipase A2 from mouse macrophages.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Secretory phospholipase A2 Type V

Secretory phospholipase A2 Type V (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids and is one of the isoforms in the growing list of the PLA2 enzyme family. This enzyme, rather than sPLA2 (Type II), is responsible for arachidonic acid mobilization leading to prostaglandin production in macrophages and mast cells. Consistent with this role, sPLA2 (Type V) is associated with the golgi apparatus, nuclear envelope, and plasma membrane in murine bone marrow-derived mast cells. sPLA2 (Type V) has been cloned from a variety of species including human, mouse and rat. The enzyme is expressed in heart, lung, placenta and spleen, as well as P388D1 macrophages and mast cells.

Alternate Names

Ca2+-dependent phospholipase A2, calcium-dependent phospholipase A2, DKFZp686C2294, EC 3.1.1.4, Group V phospholipase A2, GV-PLA2, hVPLA(2), MGC46205, Phosphatidylcholine 2-acylhydrolase 5, phospholipase A2, group V, PLA2-10

Entrez Gene IDs

18784 (Mouse)

Gene Symbol

PLA2G5

Additional Secretory phospholipase A2 Type V Products

Product Documents for Secretory phospholipase A2 Type V Antibody (3G1)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Secretory phospholipase A2 Type V Antibody (3G1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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