Semaphorin 4D/CD100 Antibody (SR1087)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22484

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22484-100ul
NBP3-22484-50ul
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Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1087

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Semaphorin 4D/CD100 Antibodies »

Product Specifications

Immunogen

A synthesized peptide derived from human Semaphorin 4D/CD100 (Uniprot #: Q92854)

Specificity

Detects endogenous levels of total Semaphorin 4D/CD100

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Semaphorin 4D/CD100 Antibody (SR1087)

Western Blot: Semaphorin 4D/CD100 Antibody (SR1087) [NBP3-22484] -

Western Blot: Semaphorin 4D/CD100 Antibody (SR1087) [NBP3-22484] - Western blot analysis using NBP3-22484 in SH-SY5Y cell lysate.

Applications for Semaphorin 4D/CD100 Antibody (SR1087)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:50-1:200

Immunohistochemistry

1:50-1:200

Western Blot

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Semaphorin 4D/CD100

Semaphorins are neuronal chemorepellants that direct pioneering neurons during nervous system development. CD100, a 150 kDa homodimer, is a novel semaphorin that induces B cells to aggregate and improves their viability in vitro. CD100 modifies CD40-CD40L B cell signaling by augmenting B cell aggregation and survival and down regulating CD23 expression. CD72 is a lymphocyte receptor for the class IV semaphorin CD100, which is involved in regulating B cell signaling. CD100 is expressed on resting and PHA stimulated T cells. The protein is weakly expressed on NK cells, EBV transformed B cells, monocytes and tumor/peripheral blood T cell lines, and at higher density on activated T cells and B cells.

Alternate Names

A8, BB18, CD100, COLL-4, M-sema-G, SEMA4D, SEMAJ

Gene Symbol

SEMA4D

Additional Semaphorin 4D/CD100 Products

Product Documents for Semaphorin 4D/CD100 Antibody (SR1087)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Semaphorin 4D/CD100 Antibody (SR1087)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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