Serotonin N-acetyltransferase [p Thr29] Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NB120-3439

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NB120-3439
NB120-3439-25ug
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Serotonin N-acetyltransferase Antibodies »

Product Summary for Serotonin N-acetyltransferase [p Thr29] Antibody - BSA Free

Immunogen

Synthetic Peptide: C(24) Q R R H T(p) L P A S(33)

Modification

p Thr29

Specificity

NB120-3439 detects phospho serotonin N-acetyltransferase (AA-NAT) from rat tissues.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Serotonin N-acetyltransferase [p Thr29] Antibody - BSA Free

Western Blot: Serotonin N-acetyltransferase [p Thr29] AntibodyBSA Free [NB120-3439]

Western Blot: Serotonin N-acetyltransferase [p Thr29] AntibodyBSA Free [NB120-3439]

Western Blot: Serotonin N-acetyltransferase [p Thr29] Antibody [NB120-3439] - Analysis of phospho AA-NAT in transfected 293T cell lysate.

Applications for Serotonin N-acetyltransferase [p Thr29] Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Western Blot

0.5 ug/ml
Application Notes
WB: Detects an approx. 23 kDa protein representing phospho AA-NAT in rat pineal gland whole protein extract.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Serotonin N-acetyltransferase

Pineal gland Serotonin N-acetyltransferase (Arylalkylamine N-acetyltransferase, AA-NAT) is an ~23 kDa protein which is the rate-limiting enzyme in melatonin synthesis. Melatonin serves as the hormonal signal of the daily light / dark cycle, or body clock. The nocturnal oscillation in enzyme activity ranges by 10- to 100-fold depending on species among vertebrates. Studies have shown that AA-NAT is regulated by cAMP at both the mRNA and protein levels. AA-NAT has putative protein kinase A (PKA) sites at Thr 29 and Ser 206. Phosphorylation of AA-NAT at these residues might play a role in protein inactivation via proteasome-dependent degradation.

Alternate Names

AA-NAT, aralkylamine N-acetyltransferaseEC 2.3.1.87, arylalkylamine N-acetyltransferase, Serotonin acetylase, SNATserotonin N-acetyltransferase

Gene Symbol

AANAT

Additional Serotonin N-acetyltransferase Products

Product Documents for Serotonin N-acetyltransferase [p Thr29] Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Serotonin N-acetyltransferase [p Thr29] Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.