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Serpin A6/Cortisol Binding Globulin Antibody (C7)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-41410

Novus Biologicals, part of Bio-Techne
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NBP3-41410

Key Product Details

Species Reactivity

Rat

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # C7

Concentration

1 mg/ml

Product Specifications

Immunogen

Immunized with recombinant Rat Serpin A6/Cortisol Binding Globulin (Uniprot#: P31211; Lys173-Leu344 (Uniprot#: P31211)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for Serpin A6/Cortisol Binding Globulin Antibody (C7)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

5-20ug/mL

Immunohistochemistry

5-20ug/mL

Western Blot

0.01-2ug/mL
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

0.01M PBS, pH7.4, 50% glycerol

Preservative

0.05% Proclin 300

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Serpin A6

Corticol binding globulin (CBG or transcotin) binds with high affinity to cortisol in plasma. Cortisol is the most potent glucocorticoid produced by the human adrenal. It is synthesized from cholesterol and its production is stimulated by pituitary adrenocorticotropic hormone (ACTH) which is regulated by corticotropin releasing factor (CRF). ACTH and CRF secretions are inhibited by high cortisol levels in a negative feedback loop. Cortisol acts through specific intracellular receptors and affects numerous physiologic systems including immune function, glucose counter regulation, vascular tone, and bone metabolism.

Alternate Names

CBG

Gene Symbol

SERPINA6

Additional Serpin A6 Products

Product Documents for Serpin A6/Cortisol Binding Globulin Antibody (C7)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Serpin A6/Cortisol Binding Globulin Antibody (C7)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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