Serpin A7/TBG Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86963

Novus Biologicals, part of Bio-Techne
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NBP1-86963
NBP1-86963-25ul
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Serpin A7/TBG Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YSKNALALFVLPKEGQMESVEAAMSSKTLKKWNRLLQKGWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADFSGLTEDNGLKLSNAAHKAVLHIGEKGTEAAAVPEVELSDQPENTFLHPIIQIDRSFMLLILERSTRSILFLGKVV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Serpin A7/TBG Antibody

Western Blot: Serpin A7/TBG Antibody [NBP1-86963]

Western Blot: Serpin A7/TBG Antibody [NBP1-86963]

Western Blot: Serpin A7/TBG Antibody [NBP1-86963] - Lane 1: Marker [kDa] 230, 110, 82, 49, 32, 26, 18. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted)
Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP1-86963]

Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP1-86963]

Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP1-86963] - Staining of human kidney shows cytoplasmic and extracellular positivity in cells of tubules.
Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP1-86963]

Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP1-86963]

Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP1-86963] - Staining of human liver shows cytoplasmic positivity in hepatocytes.

Applications for Serpin A7/TBG Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Serpin A7/TBG

Thyroxine Binding Globulin (TBG) is one of three proteins responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 triiodothyronine (T3) in the bloodstream, along with transthyretin and albumin. TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG is synthesized primarily in the liver.

Alternate Names

TBG

Gene Symbol

SERPINA7

Additional Serpin A7/TBG Products

Product Documents for Serpin A7/TBG Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Serpin A7/TBG Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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