Serpin A7/TBG Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98256

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Mouse

Applications

ELISA, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Serpin A7/TBG Antibodies »

Product Specifications

Immunogen

Produced in rabbits immunized with purified, recombinant Mouse Serpin A7/TBG (Accession#: NP_808588.3; Met 1-Gln 418)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for Serpin A7/TBG Antibody

Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP2-98256]

Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP2-98256]

Immunohistochemistry-Paraffin: Serpin A7/TBG Antibody [NBP2-98256] - Immunochemical staining of mouse Serpin A7/TBG in mouse liver with rabbit polyclonal antibody (1:1000, formalin-fixed paraffin embedded sections). Positive staining was localized to hepatocyte.

Applications for Serpin A7/TBG Antibody

Application
Recommended Usage

ELISA

1:5000-1:10000

Immunohistochemistry-Paraffin

1:500-1:2000

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Serpin A7/TBG

Thyroxine Binding Globulin (TBG) is one of three proteins responsible for carrying the thyroid hormones thyroxine (T4) and 3,5,3 triiodothyronine (T3) in the bloodstream, along with transthyretin and albumin. TBG has the highest affinity for T4 and T3, but is present in the lowest concentration of the three proteins. Despite its low concentration, TBG carries the majority of T4 in serum. Due to the very low serum concentration of T4 & T3, TBG is rarely more than 25% saturated with ligand. Unlike transthyretin and albumin, TBG has a single binding site for T4/T3. Genomically, TBG is a serpin, although it has no inhibitory function like many other members of this class of proteins. TBG is synthesized primarily in the liver.

Alternate Names

TBG

Gene Symbol

SERPINA7

Additional Serpin A7/TBG Products

Product Documents for Serpin A7/TBG Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Serpin A7/TBG Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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