Serpin I1/Neuroserpin Antibody (1D10)

Novus Biologicals, part of Bio-Techne | Catalog # H00005274-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin, Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # 1D10

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Serpin I1 Antibodies »

Product Specifications

Immunogen

SERPINI1 (AAH18043, 17 a.a. ~ 410 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TGATFPEEAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQEEIRHSMGYDSLKNGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFSQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEVPLATLEPLVKAQLVEEWANSVKKQKVEVYLPRFTVEQEIDLKDVLKALGITEIFIKDANLTGLYDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISRMAVLYPQVIVDHPFFFLIRNRRTGTILFMGRVMHPETMNTSGHDFEEL

Specificity

SERPINI1 - serpin peptidase inhibitor, clade I (neuroserpin), member 1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Serpin I1/Neuroserpin Antibody (1D10)

Western Blot: Serpin I1/Neuroserpin Antibody (1D10) [H00005274-M01]

Western Blot: Serpin I1/Neuroserpin Antibody (1D10) [H00005274-M01]

Western Blot: Serpin I1/Neuroserpin Antibody (1D10) [H00005274-M01] - SERPINI1 monoclonal antibody (M01), clone 1D10 Analysis of SERPINI1 expression in HeLa.
Immunohistochemistry-Paraffin: Serpin I1/Neuroserpin Antibody (1D10) [H00005274-M01]

Immunohistochemistry-Paraffin: Serpin I1/Neuroserpin Antibody (1D10) [H00005274-M01]

Immunohistochemistry-Paraffin: Serpin I1/Neuroserpin Antibody (1D10) [H00005274-M01] - Analysis of monoclonal antibody to SERPINI1 on formalin-fixed paraffin-embedded human cerebral cortex. Antibody concentration 3 ug/ml.
Sandwich ELISA: Serpin I1/Neuroserpin Antibody (1D10) [H00005274-M01] - Detection limit for recombinant GST tagged SERPINI1 is approximately 0.3ng/ml as a capture antibody.

Applications for Serpin I1/Neuroserpin Antibody (1D10)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against cell lysate and recombinant protein for WB. It has also been used for IHC-P and ELISA.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Serpin I1

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Alternate Names

Neuroserpin, PI12

Entrez Gene IDs

5274 (Human)

Gene Symbol

SERPINI1

OMIM

602445 (Human)

UniProt

AAH18043

Additional Serpin I1 Products

Product Documents for Serpin I1/Neuroserpin Antibody (1D10)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Serpin I1/Neuroserpin Antibody (1D10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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