SESN3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # H00143686-D01P

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SESN3 Antibodies »

Product Specifications

Immunogen

SESN3 (AAH17296.1, 1 a.a. - 321 a.a.) full-length human protein. MNRGGGSPSAAANYLLCTNCRKVLRKDKRIRVSQPLTRGPSAFIPEKEVVQANTVDERTNFLVEEYSTSGRLDNITQVMSLHTQYLESFLRSQFYMLRMDGPLPLPYRHYIAIMAAARHQCSYLINMHVDEFLKTGGIAEWLNGLEYVPQRLKNLNEINKLLAHRPWLITKEHIQKLVKTGENNWSLPELVHAVVLLAHYHALASFVFGSGINPERDPEISNGFRLISVNNFCVCDLANDNNIENASLSGSNFGIVDSLSELEALMERMKRLQEEREDEEASQEEMSTRFEKEKKESLFVVSGDTFHSFPHSGAFLHFFAF

Specificity

Reacts with sestrin 3.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SESN3 Antibody

Western Blot: SESN3 Antibody [H00143686-D01P]

Western Blot: SESN3 Antibody [H00143686-D01P]

Western Blot: SESN3 Antibody [H00143686-D01P] - Analysis of SESN3 expression in transfected 293T cell line by SESN3 polyclonal antibody.Lane 1: SESN3 transfected lysate(36.60 KDa).Lane 2: Non-transfected lysate.

Applications for SESN3 Antibody

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
This antibody is reactive against transfected lysate in western blot, and as a detection antibody in ELISA.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: SESN3

Sestrin 3 (SESN3) is a member of the sestrin family of proteins, which modulate peroxide signaling and antioxident defense. p53, a tumor suppressor, regulates the expression of proteins in this family. SESN3 is a promising target for selectively killing cancer cells containing high levels of AKT, a protein kinase that is hyperactivated in cancer cells. AKT is involved in cell proliferation and protects cells from apoptosis.

Alternate Names

SEST3MGC29667, sestrin 3, sestrin-3

Entrez Gene IDs

143686 (Human)

Gene Symbol

SESN3

UniProt

AAH17296.1 (Human)

Additional SESN3 Products

Product Documents for SESN3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SESN3 Antibody

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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