SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NLS5534

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human, Bat, Monkey, Primate

Predicted:

Bovine (94%), Canine (94%), Equine (94%), Rabbit (94%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1.0 mg/ml

View all SF-1/NR5A1 Antibodies »

Product Specifications

Immunogen

Synthetic 17 amino acid peptide from internal region of human SF-1/NR5A1/Steroidogenic Factor 1.

Epitope

internal domain of human

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Mouse (88%), Rat (88%), Hamster (88%), Turkey (82%), Chicken (82%), Xenopus (82%).

Specificity

Human NR5A1. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except TRIM23 (47%).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

Product can be stored undiluted at 4C for up to 1 month.

Scientific Data Images for SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free

Immunohistochemistry-Paraffin: SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free [NLS5534]

Immunohistochemistry-Paraffin: SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free [NLS5534]

Immunohistochemistry-Paraffin: SF-1/NR5A1/Steroidogenic Factor 1 Antibody [NLS5534] - Analysis of anti-NR5A1 antibody with human ovary.
SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free

Immunohistochemistry-Paraffin: SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free [NLS5534] -

Immunohistochemistry-Paraffin: SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free [NLS5534] - Immunohistochemistry of formalin-fixed, paraffin-embedded Human Adrenal tissue

Applications for SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry-Paraffin

1:100
Application Notes
.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.

Background: SF-1/NR5A1

Steroidogenic factor 1 (SF-1), a NR5 Fushi Tarazu-Like Receptor, has been shown to affect sexual differentiation, steroid metabolism, and neural development. SF-1 binds as a monomer and regulates all steroidogenic p450 genes, Mullerian inhibiting substance, the gonadotrophins, the ACTH receptor, oxytocin, nuclear receptor DAX-1, and several other genes. Four alternatively spliced isoforms of SF-1 have been isolated in mice, and they differ at the N and C termini but are identical in the DNA-binding domain. SF-1 expression has been documented in human brain, adrenal, spleen, liver, heart, ovary, testis, and placenta. ESTs have been isolated from human tissue libraries, including cancerous adrenal and normal lung and testis.

Long Name

Steroidogenic Factor 1

Alternate Names

AD4BP, FTZF1, NR5A1, SF1

Entrez Gene IDs

2516 (Human)

Gene Symbol

NR5A1

Additional SF-1/NR5A1 Products

Product Documents for SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SF-1/NR5A1/Steroidogenic Factor 1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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