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SG2NA Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80763

Novus Biologicals, part of Bio-Techne
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NBP1-80763

Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Mouse (95%), Rat (94%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: YEPNVLAGTLVGHTDAVWGLAYSGIKNQLLSCSADGTVRLWNPQEKLPCICTYNGDKKHGIPTSVDFIGCDPAHMVTSFNTGSAVIYDLETSQSLVILSSQVDSGLQSNNHINRVVSHPTLPVTITAHEDRHIKFFDNKTGKMI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

87 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SG2NA Antibody

Western Blot: SG2NA Antibody [NBP1-80763]

Western Blot: SG2NA Antibody [NBP1-80763]

Western Blot: SG2NA Antibody [NBP1-80763] - Analysis using Anti-STRN3 antibody NBP1-80763 (A) shows similar pattern to independent antibody NBP1-80764 (B).
Immunocytochemistry/ Immunofluorescence: SG2NA Antibody [NBP1-80763]

Immunocytochemistry/ Immunofluorescence: SG2NA Antibody [NBP1-80763]

Immunocytochemistry/Immunofluorescence: SG2NA Antibody [NBP1-80763] - Staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: SG2NA Antibody [NBP1-80763]

Immunohistochemistry-Paraffin: SG2NA Antibody [NBP1-80763]

Immunohistochemistry-Paraffin: SG2NA Antibody [NBP1-80763] - Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.

Applications for SG2NA Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF,Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SG2NA

SG2NA was identified as a human cancer autoantigen and has now been implicated in vesicular trafficking and signal transduction. It is highly related to striatin and zinedin. It is a scaffolding protein that binds PP2A A and C subunits as well as the human homolog of the yeast protein, Mob1, which has been implicated in control of mitotic progression in yeast. It also binds calmodulin and appears to modulate PP2A activity.

Alternate Names

Cell cycle autoantigen SG2NA, cell cycle S/G2 nuclear autoantigen, GS2NA, S/G2 antigen, SG2NAnuclear autoantigen, striatin, calmodulin binding protein 3, striatin-3

Entrez Gene IDs

29966 (Human)

Gene Symbol

STRN3

UniProt

Additional SG2NA Products

Product Documents for SG2NA Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SG2NA Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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