SH2B2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-22515

Novus Biologicals, part of Bio-Techne
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NBP2-22515
NBP2-22515-0.025mg
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Key Product Details

Species Reactivity

Mouse

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SH2B2 Antibodies »

Product Specifications

Immunogen

Synthetic peptide corresponding to residues E(605) A T L G R A R A V E N Q Y S(619) from mouse APS.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SH2B2 Antibody

Western Blot: SH2B2 Antibody [NBP2-22515]

Western Blot: SH2B2 Antibody [NBP2-22515]

Western Blot: SH2B2 Antibody [NBP2-22515] - Analysis of APS from 3T3-L1 cell lysate.

Applications for SH2B2 Antibody

Application
Recommended Usage

Western Blot

1:500
Application Notes
WB: Detects an approx. 84 kDa protein representing APS from recombinant mouse protein and 3T3L1 extracts.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS with 1 mg/ml BSA

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SH2B2

APS (adapter protein with Pleckstrin homology and Src homology 2 domains) is a member of the Lnk family, an adapter protein that is involved in B cell signaling, insulin signaling and cytoskeletal reorganization. A PH and an SH2 domain containing adapter protein that links activated tyrosine kinases to signaling pathways. It is tyrosine phosphorylated by JAK2, KIT and other kinases during B cell receptor stimulation of many different cytokines, chemokines and leukokines. APS has been shown to inhibit the JAK STAT pathway in collaboration with cCbl.

Alternate Names

adaptor protein with pleckstrin homology and src homology 2 domains, APSAdapter protein with pleckstrin homology and Src homology 2 domains, SH2 and PH domain-containing adapter protein APS, SH2B adapter protein 2, SH2B adaptor protein 2

Entrez Gene IDs

23921 (Mouse)

Gene Symbol

SH2B2

Additional SH2B2 Products

Product Documents for SH2B2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SH2B2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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