SHC2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87076

Novus Biologicals, part of Bio-Techne
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NBP1-87076
NBP1-87076-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SHC2 Antibodies »

Product Summary for SHC2 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: EHLYVNTQGLDAPEPEDSPKKDLFDMRPFEDALKLHECSVAAGVTAAPLPLEDQWPSPPTRRAPVAPTEEQLRQEPWYHGRMSRRAAERMLRADGD

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (82%), Rat (85%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SHC2 Antibody

Western Blot: SHC2 Antibody [NBP1-87076]

Western Blot: SHC2 Antibody [NBP1-87076]

Western Blot: SHC2 Antibody [NBP1-87076] - Lane 1: Marker [kDa] 229, 112, 84, 48, 32, 27, 17. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue
Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076]

Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076]

Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076] - Staining of human prostate shows moderate cytoplasmic positivity in glandular cells.
Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076]

Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076]

Immunohistochemistry-Paraffin: SHC2 Antibody [NBP1-87076] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.
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Applications for SHC2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SHC2

Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons

Alternate Names

neuronal Shc adaptor homolog, Protein Sck, SCKSH2 domain protein C2, SHC (Src homology 2 domain containing) transforming protein 2, SHCBSHC-transforming protein B, SHC-transforming protein 2, SLI, Src homology 2 domain-containing-transforming protein C2

Gene Symbol

SHC2

Additional SHC2 Products

Product Documents for SHC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SHC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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