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Shugoshin Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55825

Novus Biologicals, part of Bio-Techne
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NBP2-55825
NBP2-55825-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: TASVNYKEPTLASKLRRGDPFTDLCFLNSPIFKQKKDLRRSKKRALEVSPAKEAIFILYYVREFVSRFPDCRKCKLETH

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Shugoshin Antibody

Immunohistochemistry-Paraffin: Shugoshin Antibody [NBP2-55825]

Immunohistochemistry-Paraffin: Shugoshin Antibody [NBP2-55825]

Immunohistochemistry-Paraffin: Shugoshin Antibody [NBP2-55825] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: Shugoshin Antibody [NBP2-55825]

Immunohistochemistry-Paraffin: Shugoshin Antibody [NBP2-55825]

Immunohistochemistry-Paraffin: Shugoshin Antibody [NBP2-55825] - Immunohistochemical staining of human tonsil shows moderate nuclear positivity in a subset of germinal center cells.
Immunohistochemistry-Paraffin: Shugoshin Antibody [NBP2-55825]

Immunohistochemistry-Paraffin: Shugoshin Antibody [NBP2-55825]

Immunohistochemistry-Paraffin: Shugoshin Antibody [NBP2-55825] - Staining of human endometrium shows low expression as expected.

Applications for Shugoshin Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Shugoshin

Shugoshin (Sgo) proteins constitute a conserved protein family defined as centromeric protectors of Rec8-containing cohesin complexes in meiosis. It has been demonstrated that vertebrate shugoshin is required for preserving centromeric cohesion during mitosis. The presence of human Scc1 at centromeres in mitosis is dependent on human Sgo1.

Alternate Names

FLJ14230, hSgo1, NY-BR-85, Serologically defined breast cancer antigen NY-BR-85, SGO, SGO1, shugoshin 1AB protein, shugoshin 1CD protein, shugoshin 1EF protein, shugoshin 1GH protein, shugoshin 1KL protein, shugoshin-like 1, shugoshin-like 1 (S. pombe)

Gene Symbol

SGO1

Additional Shugoshin Products

Product Documents for Shugoshin Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Shugoshin Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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