The protein encoded by this gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.

Long Name

Signal-regulatory Protein beta 1

Alternate Names

CD172b, SIRPB1

Gene Symbol

SIRPB1

Additional SIRP beta 1/CD172b Products

Product Documents for SIRP beta 1/CD172b Antibody (010) [mFluor Violet 450 SE]

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Product Specific Notices for SIRP beta 1/CD172b Antibody (010) [mFluor Violet 450 SE]

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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SIRP beta 1/CD172b Antibody (010) [mFluor Violet 450 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90729MFV450

Key Product Details

Species Reactivity

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Product Summary for SIRP beta 1/CD172b Antibody (010) [mFluor Violet 450 SE]

Immunogen

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Host

Isotype

Applications for SIRP beta 1/CD172b Antibody (010) [mFluor Violet 450 SE]

ELISA

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Stability & Storage

Background: SIRP beta 1/CD172b