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SKA2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-32443

Novus Biologicals, part of Bio-Techne
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NBP2-32443
NBP2-32443-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for SKA2 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: EAEVDKLELMFQKAESDLDYIQYRLEYEIKTNHPDSASEKNPVTLLKELSVIKS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SKA2 Antibody

Immunohistochemistry-Paraffin: SKA2 Antibody [NBP2-32443]

Immunohistochemistry-Paraffin: SKA2 Antibody [NBP2-32443]

Immunohistochemistry-Paraffin: SKA2 Antibody [NBP2-32443] - Staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

Applications for SKA2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SKA2

SKA2 has been identified as part of a spindle and kinetochore complex that contains at least one other protein, SKA1. The two proteins directly interact with each other. Both are required for proper mitotic progression. During prometaphase the complex associates with the kinetochores afer microtubule attachment. Data suggests that the complex is needed to maintain chromosome alignment along the metaphase plate and for checkpoint signaling.

Alternate Names

FAM33A, family with sequence similarity 33, member A, FLJ12758, MGC110975, spindle and kinetochore associated complex subunit 2, spindle and kinetochore-associated protein 2, spindle and KT (kinetochore) associated 2

Gene Symbol

SKA2

Additional SKA2 Products

Product Documents for SKA2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SKA2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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