Slap Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80744

Novus Biologicals, part of Bio-Techne
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NBP1-80744
NBP1-80744-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Mouse

Predicted:

Mouse (93%), Rat (95%). Backed by our 100% Guarantee.

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Slap Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: MGNSMKSTPAPAERPLPNPEGLDSDFLAVLSDYPSPDISPPIFRRGEKLRVISDEGGWWKAISLSTGRESYIPGICVARVYHGWLFEGLGRDKAEELLQLPDTKVGSFMIRESETKKGFYS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Slap Antibody

Immunohistochemistry-Paraffin: Slap Antibody [NBP1-80744]

Immunohistochemistry-Paraffin: Slap Antibody [NBP1-80744]

Immunohistochemistry-Paraffin: Slap Antibody [NBP1-80744] - Staining of human lung shows strong cytoplasmic positivity in macrophages.

Applications for Slap Antibody

Application
Recommended Usage

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Slap

Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins

Alternate Names

hSLAP, SLA1, SLAP, SLAP1, SLAP-1, Src-like-adapter, Src-like-adapter protein 1, Src-like-adaptor

Entrez Gene IDs

6503 (Human)

Gene Symbol

SLA

UniProt

Q13239 (Human)

Additional Slap Products

Product Documents for Slap Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Slap Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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