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Slap Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56463

Novus Biologicals, part of Bio-Techne
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NBP2-56463
NBP2-56463-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: PCLTQSTAAPAVRASSSPVTLRQKTVDWRRVSRLQEDPEGTENPLGVDESLFSYGLRESIASYLSLTSEDNTSFDRKKKSISLMYGGSKRKSSFFSSPP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Slap Antibody

Immunocytochemistry/ Immunofluorescence: Slap Antibody [NBP2-56463]

Immunocytochemistry/ Immunofluorescence: Slap Antibody [NBP2-56463]

Immunocytochemistry/Immunofluorescence: Slap Antibody [NBP2-56463] - Staining of human cell line NB-4 shows localization to nuclear membrane. Antibody staining is shown in green.

Applications for Slap Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Slap

Adapter protein, which negatively regulates T-cell receptor (TCR) signaling. Inhibits T-cell antigen-receptor induced activation of nuclear factor of activated T-cells. Involved in the negative regulation of positive selection and mitosis of T-cells. May act by linking signaling proteins such as ZAP70 with CBL, leading to a CBL dependent degradation of signaling proteins

Alternate Names

hSLAP, SLA1, SLAP, SLAP1, SLAP-1, Src-like-adapter, Src-like-adapter protein 1, Src-like-adaptor

Gene Symbol

SLA

Additional Slap Products

Product Documents for Slap Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Slap Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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