SLBP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-57135

Novus Biologicals, part of Bio-Techne
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NBP1-57135
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all SLBP Antibodies »

Product Specifications

Immunogen

Synthetic peptides corresponding to SLBP(stem-loop (histone) binding protein) The peptide sequence was selected from the middle region of SLBP. Peptide sequence INYGKNTIAYDRYIKEVPRHLRQPGIHPKTPNKFKKYSRRSWDQQIKLWK. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for SLBP Antibody

Western Blot: SLBP Antibody [NBP1-57135]

Western Blot: SLBP Antibody [NBP1-57135]

Western Blot: SLBP Antibody [NBP1-57135] - HepG2 cell lysate, concentration 0.2-1 ug/ml.

Immunohistochemistry-Paraffin: SLBP Antibody [NBP1-57135] -

Immunohistochemistry-Paraffin: SLBP Antibody [NBP1-57135] - Formalin Fixed Paraffin; Embedded Tissue: Human Bronchial Epithelial Tissue; Observed Staining: Cytoplasmic; Primary Antibody Concentration: 1:100

Applications for SLBP Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLBP

SLBP binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.This gene encodes a protein that binds to the stem-loop structure in replication-dependent histone mRNAs. Histone mRNAs do not contain introns or polyadenylation signals, and are processed by endonucleolytic cleavage. The stem-loop structure is essential for efficient processing but this structure also controls the transport, translation and stability of histone mRNAs. Expression of the protein is regulated during the cell cycle, increasing more than 10-fold during the latter part of G1.

Alternate Names

histone, histone binding protein, histone RNA hairpin-binding protein, histone stem-loop binding protein, Histone stem-loop-binding protein, stem-loop binding protein

Gene Symbol

SLBP

UniProt

Q14493 (Human)

Additional SLBP Products

Product Documents for SLBP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SLBP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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