SLC26A5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-59791

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all SLC26A5 Antibodies »

Product Summary for SLC26A5 Antibody

Immunogen

Synthetic peptides corresponding to SLC26A5(solute carrier family 26, member 5 (prestin)) The peptide sequence was selected from the middle region of SLC26A5. Peptide sequence FSVTISMAKTLANKHGYQVDGNQELIALGLCNSIGSLFQTFSISCSLSRS. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

81 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for SLC26A5 Antibody

Western Blot: SLC26A5 Antibody [NBP1-59791]

Western Blot: SLC26A5 Antibody [NBP1-59791]

Western Blot: SLC26A5 Antibody [NBP1-59791] - Titration: 2.5 ug/ml Positive Control: HepG2 cell lysate.
Immunohistochemistry-Paraffin: SLC26A5 Antibody [NBP1-59791]

Immunohistochemistry-Paraffin: SLC26A5 Antibody [NBP1-59791]

Immunohistochemistry-Paraffin: SLC26A5 Antibody [NBP1-59791] - Human Lung Alveolar cells (indicated with arrows), 4-8ug/ml.

Applications for SLC26A5 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC26A5

SLC26A5 is a member of the SLC26A/SulP transporter family. SLC26A5 is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in its gene have been associated with non-syndromic hearing loss.This gene is a member of the SLC26A/SulP transporter family. It encodes a protein that is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in this gene have been associated with non-syndromic hearing loss. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Alternate Names

DFNB61PRESprestin (motor protein), MGC118886, MGC118887, MGC118888, MGC118889, prestin, Solute carrier family 26 member 5, solute carrier family 26, member 5 (prestin)

Gene Symbol

SLC26A5

UniProt

P58743 (Human)

Additional SLC26A5 Products

Product Documents for SLC26A5 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SLC26A5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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