SLC6A2/NET/Noradrenaline transporter Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-12251

Novus Biologicals, part of Bio-Techne
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NBP3-12251
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SLC6A2/NET Antibodies »

Product Summary for SLC6A2/NET/Noradrenaline transporter Antibody

Immunogen

Synthetic peptide corresponding to N-terminal amino acids that are unique to noradrenaline transporter protein. The antibodies are raised utilizing linear, multiple antigenic peptides or cyclic peptide methodology.

Clonality

Polyclonal

Host

Rabbit

Scientific Data Images for SLC6A2/NET/Noradrenaline transporter Antibody

Western Blot: SLC6A2/NET/Noradrenaline transporter Antibody [NBP3-12251]

Western Blot: SLC6A2/NET/Noradrenaline transporter Antibody [NBP3-12251]

Western Blot: SLC6A2/NET/Noradrenaline transporter Antibody [NBP3-12251] - Rat brain cortical membranes. 1:250 antibody in DiluObuffer. Apparent MW is 80 KDa.
Immunohistochemistry-Paraffin: SLC6A2/NET/Noradrenaline transporter Antibody [NBP3-12251]

Immunohistochemistry-Paraffin: SLC6A2/NET/Noradrenaline transporter Antibody [NBP3-12251]

Immunohistochemistry-Paraffin: SLC6A2/NET/Noradrenaline transporter Antibody [NBP3-12251] - Rat brain. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 5X magnfication.
Immunohistochemistry-Paraffin: SLC6A2/NET/Noradrenaline transporter Antibody [NBP3-12251]

Immunohistochemistry-Paraffin: SLC6A2/NET/Noradrenaline transporter Antibody [NBP3-12251]

Immunohistochemistry-Paraffin: SLC6A2/NET/Noradrenaline transporter Antibody [NBP3-12251] - Rat brain. 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40X magnfication.

Applications for SLC6A2/NET/Noradrenaline transporter Antibody

Application
Recommended Usage

ELISA

1:4000

Immunocytochemistry/ Immunofluorescence

1:100

Immunohistochemistry

1:100

Immunohistochemistry-Paraffin

1:100

Immunoprecipitation

1:200

Western Blot

1:250
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC6A2/NET

Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression (Klimek et al., 1997). Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD (Kim et al., 2006).

Long Name

Norepinephrine Transporter

Alternate Names

NAT1, Noradrenalin Transporter, Norepinephrine Transporter

Gene Symbol

SLC6A2

Additional SLC6A2/NET Products

Product Documents for SLC6A2/NET/Noradrenaline transporter Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SLC6A2/NET/Noradrenaline transporter Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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