SLC7A5/LAT1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33662

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP2-33662
NBP2-33662-25ul
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SLC7A5/LAT1 Antibodies »

Product Summary for SLC7A5/LAT1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AEEKEEAREKMLAAKSADGSAPAGEGEGVTLQRNI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SLC7A5/LAT1 Antibody

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody [NBP2-33662]

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody [NBP2-33662]

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody [NBP2-33662] - Staining of human testis shows strong membranous positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody [NBP2-33662]

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody [NBP2-33662]

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody [NBP2-33662] - Staining of human cerebellum shows strong membranous positivity in endothelial cells, as well as moderate immunoreactivity in neuropil.
Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody [NBP2-33662]

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody [NBP2-33662]

Immunohistochemistry-Paraffin: SLC7A5/LAT1 Antibody [NBP2-33662] - Staining of human liver shows no positivity in hepatocytes as expected.
View 1 more images

Applications for SLC7A5/LAT1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLC7A5/LAT1

Mammalian cells have several amino acid transport systems. These systems have been defined by both activity and specific genes. L-type amino acid transporter 1 (LAT1) is a 12 membrane-spanning protein. LAT1 is a Na + -independent neutral amino acid transporter agency and essential for the transporter of large neutral amino acid such as Leucine, Isoleucine, and Valine through the plasma membrane. LAT1 has been proposed to be one of the major nutrient transport systems at the blood-brain barrier. Drugs such as L Dopa are transported by LAT1. LAT1 is thought to be up-regulated to support the high protein synthesis for cell growth in some tumor cell lines.

Long Name

Solute Carrier Family 7 Member 5

Alternate Names

4F2LC, CD98lc, E16, LAT1, MPE16, TA1

Gene Symbol

SLC7A5

UniProt

Q01650

Additional SLC7A5/LAT1 Products

Product Documents for SLC7A5/LAT1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SLC7A5/LAT1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.