SLFN12 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76252

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all SLFN12 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 12 amino acid synthetic peptide from near the carboxy terminus human SLFN12. The immunogen is located within the last 50 amino acids of SLFN12. Amino Acid Squence: FQKNDKKMFKS

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SLFN12 Antibody - BSA Free

Western Blot: SLFN12 AntibodyBSA Free [NBP1-76252]

Western Blot: SLFN12 AntibodyBSA Free [NBP1-76252]

Western Blot: SLFN12 Antibody [NBP1-76252] - SK-N-SH cell lysate with SLFN12 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

Applications for SLFN12 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Western Blot

1 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLFN12

Despite being first described several years ago, the roles of the Schlafen (SLFN) family of proteins remain largely unknown. The SLFN genes are preferentially expressed in lymphoid tissues and differentially regulated during thymocyte maturation. It is thought that many play roles in cell growth, hemopoietic cell differentiation, and T cell development and maturation. Most members contain at least one divergent AAA domain (AAA_4) that may play a role in ATP binding. Although also known as SLFN3, a Schlafen family member that may be a marker of T cell activation, human SLFN12 has relatively low homology to SLFN3 in other species. Loss of the SLFN12 gene due to deletion is associated with Kabuki syndrome, a multiple congenital anomaly syndrome, suggesting SLFN may play a role in this genetic condition.

Alternate Names

schlafen family member 12

Gene Symbol

SLFN12

UniProt

NP_060512 (Human)

Additional SLFN12 Products

Product Documents for SLFN12 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SLFN12 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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