SLITRK1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-49541

Novus Biologicals, part of Bio-Techne
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NBP1-49541
NBP1-49541SS
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Key Product Details

Species Reactivity

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

0.65 mg/ml

View all SLITRK1 Antibodies »

Product Specifications

Immunogen

A genomic peptide made to an internal region of the human Slitrk1 protein (within residues 250-400). [Swiss-Prot Q96PX8]

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (84%).

Localization

Membrane; Single-pass type I membrane protein

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SLITRK1 Antibody - BSA Free

Western Blot: SLITRK1 AntibodyBSA Free [NBP1-49541]

Western Blot: SLITRK1 AntibodyBSA Free [NBP1-49541]

Western Blot: Slitrk1 Antibody [NBP1-49541] - Analysis of Slitrk1 in mouse brain lysate.
Immunohistochemistry: SLITRK1 Antibody - BSA Free [NBP1-49541]

Immunohistochemistry: SLITRK1 Antibody - BSA Free [NBP1-49541]

Immunohistochemistry: Slitrk1 Antibody [NBP1-49541] - Analysis of Slitrk1 in mouse prostate
Western Blot: SLITRK1 AntibodyBSA Free [NBP1-49541]

Western Blot: SLITRK1 AntibodyBSA Free [NBP1-49541]

Western Blot: Slitrk1 Antibody [NBP1-49541] - Analysis of Slitrk1 in human brain lysate.

Applications for SLITRK1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:10-1:500

Immunohistochemistry

1:250

Western Blot

1:2500
Application Notes
In Western blot a band is seen ~83 kDa.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS and 30% Glycerol

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

0.65 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SLITRK1

SLITRK1 (SLIT- and TRK-like family, member 1) is a type I transmembrane protein with an extracellular LRR (leucine-rich repeat) domain homologous to SLIT and a short intracellular domain lacking tyrosine phosphorylation motifs common among other SLITRK family members. SLITRK1 has been implicated in certain pathologies including Gilles de la Tourette syndrome (GTS) and trichotillomania (TTM). SLITRK1 has been shown to interact with 14-3-3 proteins, which are ubiquitously expressed phosphorylation-binding proteins implicated in regulation of multiple vital cellular processes such as proliferation, neuronal migration and membrane excitability. SLITRK1 has been shown to control neurite outgrowth and is expressed in embryonic as well as postembryonic brain with highest expression in cortex, thalamus and basal ganglia. SLITRK1 has also been reported to express in some astrocytic brain tumors such as astrocytomas, oligodendrogliomas, glioblastomas, gangliogliomas and primitive neuroectodermal tumors.

Long Name

SLIT and NTRK-like Family, Member 1

Alternate Names

LRRC12

Entrez Gene IDs

114798 (Human); 76965 (Mouse)

Gene Symbol

SLITRK1

UniProt

Q810C1, Q96PX8

Additional SLITRK1 Products

Product Documents for SLITRK1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SLITRK1 Antibody - BSA Free

Manufactured by Genomic Antibody Technology™. GAT FAQs

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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