Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunoprecipitation, Western Blot

Cited:

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all SMARCA6 Antibodies »

Product Specifications

Immunogen

The immunogen this antibody was made to, maps to a region between residues 550 and 600 of human Helicase, Lymphoid-Specific using the numbering given in entry NP_060533.2 (GeneID 3070).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

97 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for SMARCA6 Antibody

Western Blot: SMARCA6 Antibody [NB100-278]

Western Blot: SMARCA6 Antibody [NB100-278]

Western Blot: SMARCA6 Antibody [NB100-278] - Detection of Human HELLS by Western Blot. Samples: Whole cell lysate (50 ug) from HeLa and K562 cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-HELLS antibody NB100-278 used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Applications for SMARCA6 Antibody

Application
Recommended Usage

Immunoprecipitation

2-4 ug/mg of lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SMARCA6

HELLS, also known as LSH (lymphoid specific helicase), is a member of the SNF2 superfamily of chromatin helicases. HELLS is ubiquitously expressed and is required for the maintenance of normal DNA methylation patterns important to organism development. HELLS function has also been shown to be important to the regulation of proliferation and the expression of senescence-related genes.

Alternate Names

EC 3.6.1, EC 3.6.4.-, helicase, lymphoid-specific, LSHSWI/SNF2-related, matrix-associated, actin-dependent regulator of chromatin, Nbla10143, PASGFLJ10339, Proliferation-associated SNF2-like protein, SMARCA6lymphoid-specific helicase, subfamily A, member 6, SWI/SNF2-related matrix-associated actin-dependent regulator of chromatinsubfamily A member 6

Entrez Gene IDs

3070 (Human)

Gene Symbol

HELLS

UniProt

Q9NRZ9 (Human)

Additional SMARCA6 Products

Product Documents for SMARCA6 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SMARCA6 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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