SMARCAD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-79834

Novus Biologicals, part of Bio-Techne
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NB100-79834
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Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Immunoprecipitation

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all SMARCAD1 Antibodies »

Product Specifications

Immunogen

The immunogenfor this product falls between residues 1 and 50 of human SWI/SNFrelated matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (enhancer trap locus 1) using the numbering given in entry NP_064544.1 (GeneID 56916).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMARCAD1 Antibody

Immunoprecipitation: SMARCAD1 Antibody [NB100-79834]

Immunoprecipitation: SMARCAD1 Antibody [NB100-79834]

Immunoprecipitation: SMARCAD1 Antibody [NB100-79834] - Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-SMARCAD1/ETL1 antibody NB100-79834 used for IP at 3 mcg/mg lysate. SMARCAD1/ETL1 was also immunoprecipitated by rabbit anti-SMARCAD1/ETL1 antibody NB10-79835, which recognizes a downstream epitope. Detection: Chemiluminescence with an exposure time of 3 seconds.

Applications for SMARCAD1 Antibody

Application
Recommended Usage

Immunoprecipitation

2-5 ug/mg lysate

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SMARCAD1

The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCAD1/ETL1 is a unique member of this family in that it contains two DEAD/H box motifs, and thus is also a member of the DEAD/H-box-containing helicase superfamily. The chromosomal position of SMARCAD1 has been mapped, and it resides in a region rich in breakpoints and deletions associated with several human diseases. It is suggested to play a role in genetic instability and development.

Alternate Names

ATP-dependent helicase 1, DKFZP762K2015, EC 3.6.1, EC 3.6.4.12, HEL1, hHEL1, KIAA1122ETL1DKFZp762K2015, subfamily a, containing DEAD/H box 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A containing DEAD/H box 1, SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin

Entrez Gene IDs

56916 (Human)

Gene Symbol

SMARCAD1

UniProt

NP_064544.1 (Human)

Additional SMARCAD1 Products

Product Documents for SMARCAD1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SMARCAD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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