SMARCAD1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-79835

Novus Biologicals, part of Bio-Techne
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NB100-79835
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Validated:

Human

Cited:

Human

Predicted:

Bovine (100%), Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Validated:

Immunoprecipitation, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all SMARCAD1 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 976 and 1026 of human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (enhancer trap locus 1) using the numbering given in entry NP_064544.1 (GeneID 56916).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMARCAD1 Antibody

Western Blot: SMARCAD1 Antibody [NB100-79835]

Western Blot: SMARCAD1 Antibody [NB100-79835]

Western Blot: SMARCAD1 Antibody [NB100-79835] - Whole cell lysate (50 ug) from MDA-MB-231,MCF-7, HEK293T, U2OS, and HeLa cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-SMARCAD1/ETL1 antibody used for WB at 0.04 ug/ml. Detection: Chemiluminescencewith an exposure time of 3 minutes.
Western Blot: SMARCAD1 Antibody [NB100-79835]

Western Blot: SMARCAD1 Antibody [NB100-79835]

Western Blot: SMARCAD1 Antibody [NB100-79835] - Detection of Human and Mouse SMARCAD1/ETL1 on HeLa whole cell lysate using NB100-79835. SMARCAD1/ETL1 was also IPed by rabbit anti- SMARCAD1/ETL1 antibody NB100-79834.

Applications for SMARCAD1 Antibody

Application
Recommended Usage

Immunoprecipitation

2-10 ug/mg lysate

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SMARCAD1

The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCAD1/ETL1 is a unique member of this family in that it contains two DEAD/H box motifs, and thus is also a member of the DEAD/H-box-containing helicase superfamily. The chromosomal position of SMARCAD1 has been mapped, and it resides in a region rich in breakpoints and deletions associated with several human diseases. It is suggested to play a role in genetic instability and development.

Alternate Names

ATP-dependent helicase 1, DKFZP762K2015, EC 3.6.1, EC 3.6.4.12, HEL1, hHEL1, KIAA1122ETL1DKFZp762K2015, subfamily a, containing DEAD/H box 1, SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A containing DEAD/H box 1, SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin

Entrez Gene IDs

56916 (Human)

Gene Symbol

SMARCAD1

UniProt

Q9H4L7 (Human)

Additional SMARCAD1 Products

Product Documents for SMARCAD1 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for SMARCAD1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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