SmarcAL1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-81640

Novus Biologicals, part of Bio-Techne
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NB100-81640
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Key Product Details

Validated by

Independent Antibodies, Biological Validation

Species Reactivity

Human

Applications

Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all SmarcAL1 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 904 and 954 of human SWI/SNF-related matrix-associated actin-dependent regulator of chromatin a-like 1 using the numbering given in entry NP_054859.2 (GeneID 50485).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SmarcAL1 Antibody

Western Blot: SmarcAL1 Antibody [NB100-81640]

Western Blot: SmarcAL1 Antibody [NB100-81640]

Western Blot: SmarcAL1 Antibody [NB100-81640] - Detection of Human SMARCAL1 on HeLa whole cell lysate using NB100-81640. SMARCAL1 was also immunoprecipitated by another rabbit anti-SMARCAL1 antibody.

Applications for SmarcAL1 Antibody

Application
Recommended Usage

Immunoprecipitation

1:10-1:500

Western Blot

1:2000-1:10000

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SmarcAL1

The protein encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.

Alternate Names

ATP-driven annealing helicase, EC 3.6.1, EC 3.6.4.-, HARPSWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A-like protein 1, HepA-related protein, HHARP, SIOD, SMARCA-like protein 1, subfamily a-like 1, Sucrose nonfermenting protein 2-like 1, SWI/SNF related, matrix associated, actin dependent regulator of chromatin

Entrez Gene IDs

50485 (Human)

Gene Symbol

SMARCAL1

UniProt

NP_054859.2 (Human)

Additional SmarcAL1 Products

Product Documents for SmarcAL1 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SmarcAL1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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