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SMC1 Antibody (BL-205-2G8)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-76412

Recombinant Monoclonal Antibody.
Novus Biologicals, part of Bio-Techne
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NBP2-76412

Key Product Details

Validated by

Independent Antibodies

Species Reactivity

Validated:

Human, Mouse

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # BL-205-2G8

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for SMC1 Antibody (BL-205-2G8)

Immunogen

Immunogen sequence between amino acids 1200 and 1233 (C-Term)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMC1 Antibody (BL-205-2G8)

Western Blot: SMC1 Antibody (BL-205-2G8) [NBP2-76412]

Western Blot: SMC1 Antibody (BL-205-2G8) [NBP2-76412]

Western Blot: SMC1 Antibody (BL-205-2G8) [NBP2-76412] - Detection of human and mouse SMC1 by WB of HeLa, HEK293T, MCF-7, Hep-G2, A-549, SW620, SK-MEL-28 (SK), Jurkat, TCMK-1, NIH 3T3, and CT26 lysate. Antibody: Rabbit anti-SMC1 recombinant monoclonal [BL-205-2G8] (NBP2-76412). Secondary: HRP-conjugated goat anti-rabbit IgG.
Immunocytochemistry: SMC1 Antibody (BL-205-2G8) [NBP2-76412]

Immunocytochemistry: SMC1 Antibody (BL-205-2G8) [NBP2-76412]

Immunocytochemistry: SMC1 Antibody (BL-205-2G8) [NBP2-76412] - Detection of human SMC1 in FFPE HCT 116 cells by ICC. Antibody: Rabbit anti-SMC1 recombinant monoclonal [BL-205-2G8] (NBP2-76412). Secondary: HRP-conjugated goat anti-rabbit IgG. Substrate: DAB.
Immunohistochemistry: SMC1 Antibody (BL-205-2G8) [NBP2-76412]

Immunohistochemistry: SMC1 Antibody (BL-205-2G8) [NBP2-76412]

Immunohistochemistry: SMC1 Antibody (BL-205-2G8) [NBP2-76412] - Detection of human SMC1 in FFPE breast carcinoma by IHC. Antibody: Rabbit anti-SMC1 recombinant monoclonal [BL-205-2G8] (NBP2-76412). Secondary: HRP-conjugated goat anti-rabbit IgG. Substrate: DAB.

Applications for SMC1 Antibody (BL-205-2G8)

Application
Recommended Usage

Immunoprecipitation

20 ul/mg lysate

Western Blot

1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

Borate Buffered Saline (BBS) pH 8.2 with 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 2 - 8 C / 1 year from date of receipt

Background: SMC1

Structural maintenance of chromosomes (SMC) proteins are part of the cohesin and condensin multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. The core cohesin complex includes a heterodimer of SMC1 and SMC3 that functions by forming a ring-like structure that holds sister chromatids together. Cohesin is important to sister chromatid separation and segregation during mitosis and meiosis and also plays a role in double-strand break repair by homologous recombination.

Long Name

Structural Maintenance of Chromosomes 1

Alternate Names

SB1.8, SMC1A, SMC1L1

Gene Symbol

SMC1A

Additional SMC1 Products

Product Documents for SMC1 Antibody (BL-205-2G8)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SMC1 Antibody (BL-205-2G8)

This Product sold under License from Bethyl Laboratories, Inc.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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