Key Product Details

Validated by

Biological Validation

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all SMC2 Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residues 950 and 1000 of human Structural Maintenance of Chromosomes 2 using the numbering given in entry NP_006435.1 (GeneID 10592).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMC2 Antibody

Western Blot: SMC2 Antibody [NB100-372]

Western Blot: SMC2 Antibody [NB100-372]

Western Blot: SMC2 Antibody [NB100-372] - Samples : Whole cell lysate (90 ug) from mock transfected (E) or SMC2 transfected (T) HEK293T cells. Antibody : Affinity purified rabbit anti-SMC2 used at 0.1 ug/ml. Detection : Chemiluminescence with a 10 minute exposure.
Western Blot: SMC2 Antibody [NB100-372]

Western Blot: SMC2 Antibody [NB100-372]

Western Blot: SMC2 Antibody [NB100-372] - Whole cell lysate (90 ug) from mock transfected (E) or SMC2 transfected (T) HEK293T cells. Antibody used at 0.1 ug/ml.
Western Blot: SMC2 Antibody [NB100-372]

Western Blot: SMC2 Antibody [NB100-372]

Western Blot: SMC2 Antibody [NB100-372] - Samples: Whole cell lysate (50 ug) from HeLa and Jurkat cells prepared using NETN lysis buffer. Antibodies: Affinity purified rabbit anti-SMC2 antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.

Applications for SMC2 Antibody

Application
Recommended Usage

Western Blot

1:1
Application Notes
This antibody may be used for Western Blot, where a band at ~155 kDa is seen, representing SMC2 protein. The investigator should determine the optimal working dilution for a specific application.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SMC2

Structural Maintenance of Chromosome (SMC) proteins are required for nuclear processes, including chromosome condensation, chromatid cohesion, and DNA repair. Eukaryotic proteins are capable of binding DNA and possess a DNA-stimulated ATPase activity.

Alternate Names

CAP-E, CAPESMC2 structural maintenance of chromosomes 2-like 1 (yeast), chromosome-associated protein E, FLJ10093, hCAP-EXCAP-E homolog, SMC protein 2, SMC-2, SMC2 (structural maintenance of chromosomes 2, yeast)-like 1, SMC2 structural maintenance of chromosomes 2-like 1, SMC2L1, structural maintenance of chromosomes (SMC) family member, structural maintenance of chromosomes 2, structural maintenance of chromosomes protein 2

Entrez Gene IDs

10592 (Human)

Gene Symbol

SMC2

UniProt

NP_006435.1 (Human)

Additional SMC2 Products

Product Documents for SMC2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SMC2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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