SMC3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-19109

Novus Biologicals, part of Bio-Techne
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NBP1-19109
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Key Product Details

Validated by

Biological Validation

Species Reactivity

Validated:

Human, Mouse

Applications

Immunoprecipitation (Negative), Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.2 mg/ml

View all SMC3 Antibodies »

Product Summary for SMC3 Antibody

Immunogen

The immunogen recognized by this antibody maps to a region between residue 325 and 375 of human structural maintenance of chromosome 3 using the numbering given in entry NP_005436.1 (GeneID 9126).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMC3 Antibody

Western Blot: SMC3 Antibody [NBP1-19109]

Western Blot: SMC3 Antibody [NBP1-19109]

Western Blot: SMC3 Antibody [NBP1-19109] - Whole cell lysate from HeLa (5, 15 and 50 ug), 293T (T; 50 ug) and mouse NIH3T3 (M; 50ug) cells. Antibody used at for WB at 0.04 ug/ml.

Applications for SMC3 Antibody

Application
Recommended Usage

Western Blot

1:2000-1:10000
Application Notes
This antibody is useful for western blot. It is not recommended for immunoprecipitation.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

TBS and 0.1% BSA

Preservative

0.09% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: SMC3

This gene belongs to the SMC3 subfamily of SMC proteins. The encoded protein occurs in certain cell types as either an intracellular, nuclear protein or a secreted protein. The nuclear form, known as structural maintenance of chromosomes 3, is a component of the multimeric cohesin complex that holds together sister chromatids during mitosis, enabling proper chromosome segregation. Post-translational modification of the encoded protein by the addition of chondroitin sulfate chains gives rise to the secreted proteoglycan bamacan, an abundant basement membrane protein. [provided by RefSeq]

Alternate Names

Bamacan, BAMSMC protein 3, Basement membrane-associated chondroitin proteoglycan, BMH, Chondroitin sulfate proteoglycan 6, chondroitin sulfate proteoglycan 6 (bamacan), Chromosome-associated polypeptide, CSPG6structural maintenance of chromosomes protein 3, hCAP, HCAPbamacan, SMC-3, SMC3L1CDLS3, structural maintenance of chromosomes 3

Entrez Gene IDs

9126 (Human); 13006 (Mouse)

Gene Symbol

SMC3

UniProt

NP_005436.1 (Human)

Additional SMC3 Products

Product Documents for SMC3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SMC3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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