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SMC6L1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33378

Novus Biologicals, part of Bio-Techne
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NBP2-33378
NBP2-33378-25ul

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KEEHGKIKREELDVKHALSYNQRQLKELKDSKTDRLKRFGPNVPALLEAIDDAYRQGHFTYKPVGPLGACIHLRDPELALAIESCL

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (81%), Rat (84%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SMC6L1 Antibody

Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378]

Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378]

Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378] - Staining of human testis shows weak nuclear positivity in cells in seminiferous ducts.
Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378]

Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378]

Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378] - Staining of human placenta shows weak nuclear positivity in a subset of trophoblastic cells.
Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378]

Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378]

Immunohistochemistry-Paraffin: SMC6L1 Antibody [NBP2-33378] - Staining of human prostate shows weak nuclear positivity in glandular cells.

Applications for SMC6L1 Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SMC6L1

SMC (Structural maintenance of chromosomes) proteins are members of multisubunit complexes that play a critical role in chromosome organization, segregation, gene regulation, and DNA repair. Two of these complexes, cohesin and condensin consist of a core complex of an SMC1 and SMC3 heterodimer or an SMC2 and SMC4 heterodimer, respectively. A third complex includes a heterodimer of SMC5 and SMC6 whose function is not fully understood but is proposed to be related to DNA repair.

Alternate Names

FLJ22116, hSMC6, SMC protein 6, SMC-6, SMC6 structural maintenance of chromosomes 6-like 1, SMC6 structural maintenance of chromosomes 6-like 1 (yeast), SMC6L1FLJ35534, structural maintenance of chromosomes 6, structural maintenance of chromosomes protein 6

Gene Symbol

SMC6

UniProt

Additional SMC6L1 Products

Product Documents for SMC6L1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SMC6L1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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