SNAP23 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52065

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NBP1-52065
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Rabbit (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all SNAP23 Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-TDKADTNRDR corresponding to C-Terminus according to NP_570710.1.

Epitope

C-TDKADTNRDR

Specificity

This antibody is expected to recognize both isoforms (NP_003816.2; NP_570710.1). Amino acid numbering in name refers to NP_003816.2 sequence.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for SNAP23 Antibody

Western Blot: SNAP23 Antibody [NBP1-52065]

Western Blot: SNAP23 Antibody [NBP1-52065]

Western Blot: SNAP23 Antibody [NBP1-52065] - (0.2ug/ml) Analysis of PBMC lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for SNAP23 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:2000

Western Blot

0.2 - 0.6 ug/ml
Application Notes
WB: Approx. 20+26 kDa band bands observed in human peripheral blood mononucleocytes lysates (calculated MW of 17.8 kDa band according to NP_570710.1 and of 23.4 kDa band according to NP_003816.2).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SNAP23

Synaptosomal-associated proteins (SNAPs) are cytosolic proteins that play a key role in in the process of membrane fusion in intracellular vesicle trafficking. In eukaryotic cells, the SNARE (soluble N-ethylmaleimide-sensitive factor attachment protein receptor) complex is critical to membrane docking and fusion and is believed to impart some degree of specificity between vesicle SNARE (v-SNARE) and target organelle SNARE (t-SNARE). In neurons and neuroendocrine cells, the SNARE complex consists of the integral membrane proteins VAMP (vesicle-associated membrane protein), syntaxin and SNAP-25. In non-neuronal tissue, a SNAP-25 homolog, SNAP-23, functionally replaces SNAP-25 in the SNARE complex. Studies show that VAMP, syntaxin and SNAP-23 are required for SNARE function and that this complex exists as a heterotrimer of the three proteins. In insulin signalling pathways, studies suggest that the translocation of GLUT4 in adipocytes requires that functional SNAP-23 be present in SNARE complexes.

Long Name

Synaptosomal-associated Protein, 23kDa

Alternate Names

HsT17016, SNAP-23, SNAP23A, SNAP23B, synaptosomal-associated protein 23, synaptosomal-associated protein, 23kD, synaptosomal-associated protein, 23kDa, Vesicle-membrane fusion protein SNAP-23

Entrez Gene IDs

8773 (Human); 20619 (Mouse); 64630 (Rat)

Gene Symbol

SNAP23

UniProt

NP_003816.2 (Human)

Additional SNAP23 Products

Product Documents for SNAP23 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SNAP23 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.