SNRPB Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-56420

Novus Biologicals, part of Bio-Techne
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NBP2-56420
NBP2-56420-25ul
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Key Product Details

Validated by

Knockout/Knockdown

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Knockdown Validated, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SNRPB Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QAPAGLAGPVRGVGGPSQQVMTPQGRGT

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SNRPB Antibody

Immunocytochemistry/ Immunofluorescence: SNRPB Antibody [NBP2-56420]

Immunocytochemistry/ Immunofluorescence: SNRPB Antibody [NBP2-56420]

Immunocytochemistry/Immunofluorescence: SNRPB Antibody [NBP2-56420] - Staining of human cell line HEK 293 shows localization to nucleoplasm.
Knockdown Validated: SNRPB Antibody [NBP2-56420]

Knockdown Validated: SNRPB Antibody [NBP2-56420]

Knockdown Validated: SNRPB Antibody [NBP2-56420] - Analysis in Caco-2 cells transfected with control siRNA, target specific siRNA probe #1, using Anti-SNRPB antibody. Remaining relative intensity is presented. Loading control: Anti-GAPDH.

Applications for SNRPB Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SNRPB

SNRPB is encoded by this gene is one of several nuclear proteins that are found in common among U1, U2, U4/U6, and U5 small ribonucleoprotein particles (snRNPs). These snRNPs are involved in pre-mRNA splicing, and the encoded protein may also play a role in pre-mRNA splicing or snRNP structure. Autoantibodies from patients with systemic lupus erythematosus frequently recognize epitopes on the encoded protein. Two transcript variants encoding different isoforms (B and B') have been found for this gene.

Alternate Names

CODB polypeptide of Sm protein, Sm protein B/B', small nuclear ribonucleoprotein polypeptides B and B', small nuclear ribonucleoprotein polypeptides B and B1, small nuclear ribonucleoprotein-associated proteins B and B', SmB/B', Sm-B/B'sm-B/Sm-B', SmB/SmB', snRNP-Bsmall nuclear ribonucleoprotein polypeptide B, SNRPB1

Gene Symbol

SNRPB

Additional SNRPB Products

Product Documents for SNRPB Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SNRPB Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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