SNX26 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-53781

Novus Biologicals, part of Bio-Techne
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NB100-53781
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all SNX26 Antibodies »

Product Specifications

Immunogen

Peptide with sequence ARSTDSLDGPGE-C corresponding to N-Terminus according to NP_443180.2.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for SNX26 Antibody

Immunohistochemistry-Paraffin: SNX26 Antibody [NB100-53781]

Immunohistochemistry-Paraffin: SNX26 Antibody [NB100-53781]

Immunohistochemistry-Paraffin: SNX26 Antibody [NB100-53781] - Stainingof paraffin embedded human prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Applications for SNX26 Antibody

Application
Recommended Usage

Immunohistochemistry

1.25 ug/ml

Immunohistochemistry-Paraffin

1:10 - 1:500

Peptide ELISA

Detection limit 1:32000

Western Blot

1:100 - 1:2000
Application Notes
WB: Preliminary experiments gave an approx. 35 kDa band in human brain (hippocampus) lysates after 1 ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 121 kDa band according to NP_443180.2. The 35 kDa band was successfully blocked by incubation with the immunizing peptide. IHC-P: Human prostate shows cytoplasm staining of secretory cells in the glands.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: SNX26

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. The specific function of this protein has not been elucidated. Alternative splice variants have been described but their full length nature has not been determined. SNX26 may be involved in several stages of intracellular trafficking. It could play an important role in the regulation of glucose transport by insulin. It may act as a downstream effector of RHOQ/TC10 in the regulation of insulin-stimulated glucose transport.

Alternate Names

FLJ39019, neurite outgrowth multiadaptor RhoGAP protein, NOMA-GAP, Rho GTPase activating protein 33, rho GTPase-activating protein 33, Rho-type GTPase-activating protein 33, sorting nexin 26, Sorting nexin-26, Tc10/CDC42 GTPase-activating protein, TCGAPSNX26

Entrez Gene IDs

115703 (Human)

Gene Symbol

ARHGAP33

UniProt

NP_443180.2 (Human)

Additional SNX26 Products

Product Documents for SNX26 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SNX26 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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