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SOCS-1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-98891

Novus Biologicals, part of Bio-Techne
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NBP2-98891-100ul
NBP2-98891-50ul

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for SOCS-1 Antibody

Immunogen

Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human SOCS-1.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for SOCS-1 Antibody

Immunocytochemistry/ Immunofluorescence: SOCS-1 Antibody [NBP2-98891]

Immunocytochemistry/ Immunofluorescence: SOCS-1 Antibody [NBP2-98891]

Immunocytochemistry/Immunofluorescence: SOCS-1 Antibody [NBP2-98891] - Immunofluorescence staining of SOCS-1 in HeLa cells. Cells were fixed with 4% PFA, blocked with 10% serum. Then incubated with rabbit anti-human SOCS-1 polyclonal antibody (1:1000)(Figure A), incubated with rabbit anti-human SOCS-1 polyclonal antibody and antigen (Figure B) at 4C overnight. Then cells were stained with the Alexa Fluor(R)488-conjugated Goat Anti-rabbit IgG secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to cytoplasm and nucleus.

Applications for SOCS-1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:300-1:10000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen and protein A Affinity-purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SOCS-1

The SOCS (Suppressor of cytokine signaling) family of proteins has at least 8 members; SOCS1 to SOCS7 and CIS (cytokine inducible SH2 containing protein). SOCS1 has a role in the negative regulation of cytokines that signal through the JAK/STAT3 pathway.

Long Name

Suppressor Of Cytokine Signaling 1

Alternate Names

CIS1, Cish1, JAB, SOCS1, SSI-1, TIP3

Gene Symbol

SOCS1

Additional SOCS-1 Products

Product Documents for SOCS-1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SOCS-1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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