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SOCS-5 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-85608

Novus Biologicals, part of Bio-Techne
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NBP1-85608-25ul
NBP1-85608

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (95%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for SOCS-5 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: HLIKQHTAPVSPHSTFFDTFDPSLVSTEDEEDRLRERRRLSIEEGVDPPPNAQIHTFEATAQVNPLYKLGPKLAPGMTEISGDSSAIPQANCDSEEDTTTLCLQSRRQKQRQISGDSHTHVSRQGAWKVHTQI

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SOCS-5 Antibody

Immunocytochemistry/ Immunofluorescence: SOCS-5 Antibody [NBP1-85608]

Immunocytochemistry/ Immunofluorescence: SOCS-5 Antibody [NBP1-85608]

Immunocytochemistry/Immunofluorescence: SOCS-5 Antibody [NBP1-85608] - Staining of human cell line A-431 shows localization to plasma membrane & cytosol.
Immunohistochemistry-Paraffin: SOCS-5 Antibody [NBP1-85608]

Immunohistochemistry-Paraffin: SOCS-5 Antibody [NBP1-85608]

Immunohistochemistry-Paraffin: SOCS-5 Antibody [NBP1-85608] - Staining of human endometrium shows cytoplasmic positivity in glandular cells.
Immunocytochemistry/ Immunofluorescence: SOCS-5 Antibody [NBP1-85608]

Immunocytochemistry/ Immunofluorescence: SOCS-5 Antibody [NBP1-85608]

Immunocytochemistry/Immunofluorescence: SOCS-5 Antibody [NBP1-85608] - Staining of human cell line U-2 OS shows localization to nucleoplasm & cytosol.

Applications for SOCS-5 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:20 - 1:50

Immunohistochemistry-Paraffin

1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SOCS-5

SOCS5 is encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.

Long Name

Suppressor Of Cytokine Signaling 5

Alternate Names

CIS6, CISH5, CISH6, SOCS5

Gene Symbol

SOCS5

Additional SOCS-5 Products

Product Documents for SOCS-5 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SOCS-5 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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