Soluble Liver/Pancreas Antigen Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-57464

Novus Biologicals, part of Bio-Techne
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NBP2-57464
NBP2-57464-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (96%), Rat (96%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Soluble Liver/Pancreas Antigen Antibodies »

Product Summary for Soluble Liver/Pancreas Antigen Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: EKGKCPENGWDESTLELFLHELAIMDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRSGDISAVQPKA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Soluble Liver/Pancreas Antigen Antibody

Immunocytochemistry/ Immunofluorescence: Soluble Liver/Pancreas Antigen Antibody [NBP2-57464]

Immunocytochemistry/ Immunofluorescence: Soluble Liver/Pancreas Antigen Antibody [NBP2-57464]

Immunocytochemistry/Immunofluorescence: Soluble Liver/Pancreas Antigen Antibody [NBP2-57464] - Staining of human cell line RH-30 shows localization to vesicles.

Applications for Soluble Liver/Pancreas Antigen Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Soluble Liver/Pancreas Antigen

The 21st amino acid, selenocysteine (sec), is distinct from other amino acids because it lacks its own tRNA synthetase and is the only amino acid synthesized on its cognate tRNA. Synthesis of sec begins with acylation of tRNA(sec) (TRSP; MIM 165060) by seryl-tRNA synthetase (SARS; MIM 607529) to give ser-tRNA(sec), which is subsequently phosphorylated by O-phosphoseryl-tRNA kinase (PSTK; MIM 611310) to give O-phosphoseryl-tRNA(sec). SEPSECS catalyzes the final step of sec synthesis by converting O-phosphoseryl-tRNA(sec) to selenocysteinyl-tRNA(sec) using selenophosphate as the selenium donor (Palioura et al., 2009 (PubMed 19608919)).(supplied by OMIM)

Alternate Names

EC 2.9.1.2, EC 2.9.1.n1, Liver-pancreas antigen, LPDKFZp434B1417, MGC161491, O-phosphoseryl-tRNA(Sec) selenium transferase, Sec synthase, Selenocysteine synthase, Selenocysteinyl-tRNA(Sec) synthase, Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase, SepSecS, Sep-tRNA:Sec-tRNA synthase, SLA/LP, SLA/LP autoantigen, SLA-p35, SLAUGA suppressor tRNA-associated protein, Soluble liver antigen, soluble liver antigen/liver pancreas antigen, tRNA(Ser/Sec)-associated antigenic protein, TRNP48

Gene Symbol

SEPSECS

Additional Soluble Liver/Pancreas Antigen Products

Product Documents for Soluble Liver/Pancreas Antigen Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Soluble Liver/Pancreas Antigen Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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