Sorbitol Dehydrogenase Antibody (1C2)

Novus Biologicals, part of Bio-Techne | Catalog # H00006652-M03

Novus Biologicals, part of Bio-Techne
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H00006652-M03
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunoprecipitation, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1C2

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Sorbitol Dehydrogenase Antibodies »

Product Specifications

Immunogen

SORD (AAH21085, 1 a.a. ~ 357 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAAAAKPNNLSLVVHGPGDLRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNLSPSIFFCATPPDDGNLCRFYKHNAAFCYKLPDNVTFEEGALIEPLSVGIHACRRGGVTLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEGQLGCKPEVTIECTGAEASIQAGIYATRSGGTLVLVGLGSEMTTVPLLHAAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIMLKCDPSDQNP

Specificity

SORD - sorbitol dehydrogenase (1C2)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Sorbitol Dehydrogenase Antibody (1C2)

Western Blot: Sorbitol Dehydrogenase Antibody (1C2) [H00006652-M03]

Western Blot: Sorbitol Dehydrogenase Antibody (1C2) [H00006652-M03]

Western Blot: Sorbitol Dehydrogenase Antibody (1C2) [H00006652-M03] - Analysis of SORD expression in transfected 293T cell line by SORD monoclonal antibody (M03), clone 1C2. Lane 1: SORD transfected lysatE (38.3 KDa). Lane 2: Non-transfected lysate.
Immunoprecipitation: Sorbitol Dehydrogenase Antibody (1C2) [H00006652-M03]

Immunoprecipitation: Sorbitol Dehydrogenase Antibody (1C2) [H00006652-M03]

Immunoprecipitation: Sorbitol Dehydrogenase Antibody (1C2) [H00006652-M03] - Analysis of SORD transfected lysate using anti-SORD monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with SORD rabbit polyclonal antibody.

Applications for Sorbitol Dehydrogenase Antibody (1C2)

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Sorbitol Dehydrogenase

Sorbitol dehydrogenase (SDH), a member of the medium-chain dehydrogenase/reductase protein family and the second enzyme of the polyol pathway of glucose metabolism, converts sorbitol to fructose strictly using NAD(+) as coenzyme. SDH is expressed almost ubiquitously in all mammalian tissues. The enzyme has attracted considerable interest due to its implication in the development of diabetic complications as the polyol pathway is particularly active in hyperglycemic states. Although SORD is closely related to the class I long-chain alcohol dehydrogenases, it differs in substrate specificity, catalyzing polyols such as sorbitol and xylitol but having no activity towards primary alcohols.

Alternate Names

EC 1.1.1, EC 1.1.1.14, L-iditol 2-dehydrogenase, sorbitol dehydrogenase, SORD1

Entrez Gene IDs

6652 (Human)

Gene Symbol

SORD

UniProt

AAH21085 (Human)

Additional Sorbitol Dehydrogenase Products

Product Documents for Sorbitol Dehydrogenase Antibody (1C2)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Sorbitol Dehydrogenase Antibody (1C2)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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