SOX10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-68983

Novus Biologicals, part of Bio-Techne
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NBP1-68983-100ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

0.5 mg/ml

View all SOX10 Antibodies »

Product Specifications

Immunogen

Synthetic peptide directed towards the middle region of human SOX10 (NP_008872). Peptide sequence PGGEAEQGGTAAIQAHYKSAHLDHRHPGEGSPMSDGNPEHPSGQSHGPPT. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for SOX10 Antibody

Western Blot: SOX10 Antibody [NBP1-68983]

Western Blot: SOX10 Antibody [NBP1-68983]

Western Blot: SOX10 Antibody [NBP1-68983] - Analysis of HepG2 lysate Cell lysates, Antibody Dilution: 0.5 ug/ml.
Immunohistochemistry-Paraffin: SOX10 Antibody [NBP1-68983]

Immunohistochemistry-Paraffin: SOX10 Antibody [NBP1-68983]

Immunohistochemistry-Paraffin: SOX10 Antibody [NBP1-68983] - Human Kidney tissue, Epithelial cells of renal tubule (Indicated with Arrows) 4-8 ug/ml.
Western Blot: SOX10 Antibody [NBP1-68983]

Western Blot: SOX10 Antibody [NBP1-68983]

Western Blot: SOX10 Antibody [NBP1-68983] - HepG2, 0.25ug/ml.
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Applications for SOX10 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

4.0-8.0 ug/ml

Western Blot

1.0 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SOX10

SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.

Long Name

Transcription Factor SOX10

Alternate Names

DOM, WS4

Entrez Gene IDs

6663 (Human)

Gene Symbol

SOX10

UniProt

P56693

Additional SOX10 Products

Product Documents for SOX10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SOX10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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