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SP-B/Surfactant Protein B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33982

Novus Biologicals, part of Bio-Techne
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NBP2-33982
NBP2-33982-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: AWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SP-B/Surfactant Protein B Antibody

Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-33982]

Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-33982]

Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-33982] - Staining in human lung and kidney tissues using anti-SFTPB antibody. Corresponding SFTPB RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-33982]

Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-33982]

Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-33982] - Staining of human lung shows high expression.
Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-33982]

Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-33982]

Immunohistochemistry-Paraffin: SP-B/Surfactant Protein B Antibody [NBP2-33982] - Staining of human kidney shows low expression as expected.

Applications for SP-B/Surfactant Protein B Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SP-B/Surfactant Protein B

The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM]

Long Name

Surfactant Protein B

Alternate Names

PSP-B, SFTB3, SFTP3, SFTPB, SMDP1

Gene Symbol

SFTPB

UniProt

Additional SP-B/Surfactant Protein B Products

Product Documents for SP-B/Surfactant Protein B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for SP-B/Surfactant Protein B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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