SP140 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-80009

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1 mg/ml

View all SP140 Antibodies »

Product Specifications

Immunogen

Synthetic peptide directed towards the N terminal of human SP140. Peptide sequence PEPIFRFFRENKVEIASAITRPFPFLMGLRDRSFISEQMYEHFQEAFRNL. The peptide sequence for this immunogen was taken from within the described region.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

20 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Description

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Scientific Data Images for SP140 Antibody

Western Blot: SP140 Antibody [NBP1-80009]

Western Blot: SP140 Antibody [NBP1-80009]

Western Blot: SP140 Antibody [NBP1-80009] - Human Lung Tumor, Antibody Dilution: 0.5 ug/ml.
Immunohistochemistry-Paraffin: SP140 Antibody [NBP1-80009]

Immunohistochemistry-Paraffin: SP140 Antibody [NBP1-80009]

Immunohistochemistry-Paraffin: SP140 Antibody [NBP1-80009] - Human kidney Tissue, antibody concentration 4-8ug/ml. Cells with positive label: renal corpuscle cells (indicated with arrows) 400X magnification.
Western Blot: SP140 Antibody [NBP1-80009]

Western Blot: SP140 Antibody [NBP1-80009]

Western Blot: SP140 Antibody [NBP1-80009] - Raji Cell Lysate 5.0 ug/ml, gel concentration 12%

Applications for SP140 Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1.0 ug/ml

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS, 2% Sucrose

Preservative

0.09% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SP140

SP140 is a component of the nuclear body, also known as nuclear domain 10, PML oncogenic domain, and KR body. May be involved in the pathogenesis of acute promyelocytic leukemia and viral infection

Alternate Names

Lymphoid-restricted homolog of Sp100, lymphoid-specific SP100 homolog, LYSP100, LYSP100-A, LYSP100-B, MGC126440, Nuclear autoantigen Sp-140, nuclear body protein SP140, SP140 nuclear body protein, Speckled 140 kDa

Gene Symbol

SP140

UniProt

NP_001005176 (Human)

Additional SP140 Products

Product Documents for SP140 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for SP140 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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