SPAG8 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-39092

Novus Biologicals, part of Bio-Techne
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NBP2-39092
NBP2-39092-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all SPAG8 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: PGSGPGHGSGSHPGPASGPGPDTGPDSELSPCIPPGFRNLVADRVPNYTSWSQHCPWEPQKQPPWEFLQVLEPGARGLWKP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for SPAG8 Antibody

Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-39092]

Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-39092]

Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-39092] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-39092]

Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-39092]

Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-39092] - Staining of human prostate shows low expression as expected.
Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-39092]

Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-39092]

Immunohistochemistry-Paraffin: SPAG8 Antibody [NBP2-39092] - Staining in human testis and prostate tissues using anti-SPAG8 antibody. Corresponding SPAG8 RNA-seq data are presented for the same tissues.

Applications for SPAG8 Antibody

Application
Recommended Usage

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SPAG8

The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein encoded by this gene is recognized by sperm agglutinating antibodies from an infertile woman. This protein is localized in germ cells of the testis at all stages of spermatogenesis and is localized to the acrosomal region of mature spermatozoa. Alternatively spliced variants that encode different protein isoforms have been described but the full-length sequences of only two have been determined.

Alternate Names

BS-84, HSD-1MGC26201, hSMP-1, SMP1, SMP-1, SPAG3, sperm associated antigen 8, Sperm membrane protein 1, Sperm membrane protein BS-84, sperm-associated antigen 8

Gene Symbol

SPAG8

UniProt

Q99932 (Human)

Additional SPAG8 Products

Product Documents for SPAG8 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SPAG8 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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