SR-AI/MSR Antibody (004)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90437

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Mouse

Applications

Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 004

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all SR-AI/MSR Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Mouse SR-AI/MSR (Accession#: AAH03814.1; Trp 83-Val 354).

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for SR-AI/MSR Antibody (004)

Immunocytochemistry/ Immunofluorescence: SR-AI/MSR Antibody (004) [NBP2-90437]

Immunocytochemistry/ Immunofluorescence: SR-AI/MSR Antibody (004) [NBP2-90437]

Immunocytochemistry/Immunofluorescence: SR-AI/MSR Antibody (004) [NBP2-90437] - Confocal immunofluorescence analysis of Mouse SR-AI/MSR1 in RAW264.7 cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with Rabbit anti-Mouse SR-AI/MSR1 monoclonal antibody (1:100) at 4C overnight. Then cells were stained with the Alexa Fluor(R) 488-conjugated Goat Anti-rabbit IgG Secondary antibody (green) and counterstained with DAPI (blue). Positive staining was localized to plasma membrane.
Immunohistochemistry-Paraffin: SR-AI/MSR Antibody (004) [NBP2-90437]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody (004) [NBP2-90437]

Immunohistochemistry-Paraffin: SR-AI/MSR Antibody (004) [NBP2-90437] - Immunochemical staining of mouse SR-AI/MSR in mouse liver with rabbit monoclonal antibody (1:100, formalin-fixed paraffin embedded sections).
Flow Cytometry: SR-AI/MSR Antibody (004) [NBP2-90437]

Flow Cytometry: SR-AI/MSR Antibody (004) [NBP2-90437]

Flow Cytometry: SR-AI/MSR Antibody (004) [NBP2-90437] - Flow cytometric analysis of Mouse SR-AI/MSR expression on Raw264.7 cells. Cells were stained with purified anti-Mouse SR-AI/MSR, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.

Applications for SR-AI/MSR Antibody (004)

Application
Recommended Usage

Flow Cytometry

1:25-1:100

Immunocytochemistry/ Immunofluorescence

1:50-1:1000

Immunohistochemistry-Paraffin

1:50-1:200

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: SR-AI/MSR

Macrophage scavenger receptors (MSR) are membrane glycoproteins that mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta). While the normal role of MSR is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Abeta deposition in Alzheimer's disease (AD).

In cell cultures, macrophage scavenger receptor has been shown to mediate adhesion of macrophages and other cell lines to tissue culture plastic. MSR1 antibodies are useful for research on atherosclerosis, Alzheimer's disease, and host defense.

Long Name

Macrophage Scavenger Receptor Types I and II

Alternate Names

CD204, MSR1, SCARA1, SRAI

Gene Symbol

MSR1

Additional SR-AI/MSR Products

Product Documents for SR-AI/MSR Antibody (004)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for SR-AI/MSR Antibody (004)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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